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Drug resistance
Drug resistance is the pathological surviving mechanism when the drugs concentration is not high enough to kill all these pathogens inside the body. Therefore, the results of drug resistance are the causes of the faulty drug doses, to look for higher and higher doses or alternative to kill these surviving or further resisted pathogens. Pathogens, such as bacteria, virus, and cancer cells, with the well known of bacterial resistance for more concerns.
- Antibiotic Resistance
- In 2014, WHO has concerns the topic on globalized antibiotic resistance.
https://www.nature.com/articles/nrd4675 - This photograph has declared the two possible pathways causing drug resistance: (1) Mutation occurs while bacteria duplicates DNA. (2) Mutation occurs while DNA transportation, often occurring in cytoplasm of bacteria.
https://www.antibioticresearch.org.uk/research/antibiotic-resistance-breakers/ - Fighting to antibiotic resistance, ARBs were invented combining new and old techniques as the new antibacterial treatment.
https://www.nature.com/articles/510477a - This photograph mentions how to overcome the mechanism of antibiotic resistance.
References: Antibiotic resistance breakers: can repurposed drugs fill the antibiotic discovery void?
https://www.nature.com/articles/nrd4675 When antibiotics turn toxic
https://www.nature.com/articles/d41586-018-03267-5 To the rescue of old drugs
https://www.nature.com/articles/510477a
https://pubmed.ncbi.nlm.nih.gov/30459368/ References: A new road to cancer-drug resistance
https://pubmed.ncbi.nlm.nih.gov/30459368/
Cancer Bet on drug resistance
https://pubmed.ncbi.nlm.nih.gov/26735017/